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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
34.85
Human Site:
T165
Identified Species:
51.11
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
T165
K
C
H
E
F
T
A
T
F
F
P
Q
P
T
F
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
T165
K
C
H
E
F
T
A
T
F
F
P
Q
P
T
F
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
T628
K
N
H
E
F
I
A
T
F
F
G
Q
P
T
F
Dog
Lupus familis
XP_849292
706
81555
T165
K
C
H
E
F
T
A
T
F
F
P
Q
P
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
T165
K
C
H
E
F
T
A
T
F
F
P
Q
P
T
F
Rat
Rattus norvegicus
Q9WTQ0
707
81732
T165
K
C
H
E
F
T
A
T
F
F
P
Q
P
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
T165
K
C
H
E
F
T
A
T
F
F
P
Q
P
T
F
Chicken
Gallus gallus
NP_001006133
699
80179
T162
K
N
H
E
F
I
A
T
F
F
G
Q
P
T
F
Frog
Xenopus laevis
Q7LZQ8
671
76506
L147
C
V
M
N
V
P
S
L
C
G
T
D
H
T
E
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
R157
C
G
T
D
H
T
E
R
R
G
R
I
Q
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
H152
L
P
H
R
F
V
V
H
S
Y
K
R
F
T
F
Honey Bee
Apis mellifera
XP_394743
624
71014
H146
Q
A
C
Q
T
A
V
H
K
K
C
H
D
K
L
Nematode Worm
Caenorhab. elegans
P34722
704
80280
T171
R
G
H
Q
F
V
A
T
F
F
R
Q
P
H
F
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
K146
G
V
N
S
T
E
T
K
K
L
K
E
R
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
S359
Q
G
E
N
T
S
T
S
Q
I
S
T
N
S
W
Red Bread Mold
Neurospora crassa
P87253
1142
127954
K463
Y
G
H
K
F
V
Q
K
Q
F
Y
N
I
M
R
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
80
100
N.A.
100
100
N.A.
100
80
6.6
6.6
N.A.
26.6
0
60
0
P-Site Similarity:
100
100
80
100
N.A.
100
100
N.A.
100
80
13.3
13.3
N.A.
40
13.3
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
57
0
0
0
0
0
0
0
0
% A
% Cys:
13
38
7
0
0
0
0
0
7
0
7
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
7
7
0
0
% D
% Glu:
0
0
7
50
0
7
7
0
0
0
0
7
0
0
7
% E
% Phe:
0
0
0
0
69
0
0
0
57
63
0
0
7
7
63
% F
% Gly:
7
25
0
0
0
0
0
0
0
13
13
0
0
0
0
% G
% His:
0
0
69
0
7
0
0
13
0
0
0
7
7
7
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
7
0
7
7
7
0
% I
% Lys:
50
0
0
7
0
0
0
13
13
7
13
0
0
7
0
% K
% Leu:
7
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
13
7
13
0
0
0
0
0
0
0
7
7
0
7
% N
% Pro:
0
7
0
0
0
7
0
0
0
0
38
0
57
0
0
% P
% Gln:
13
0
0
13
0
0
7
0
13
0
0
57
7
0
0
% Q
% Arg:
7
0
0
7
0
0
0
7
7
0
13
7
7
0
7
% R
% Ser:
0
0
0
7
0
7
7
7
7
0
7
0
0
7
0
% S
% Thr:
0
0
7
0
19
44
13
57
0
0
7
7
0
63
7
% T
% Val:
0
13
0
0
7
19
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _